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Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry)
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by David J. Triggle, Murali Gopalakrishnan, David Rampe, and Wei Zheng
Sales Rank: 1527920
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$204.20
At Amazon
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Hardcover: 492 pages
Publisher: Wiley-VCH; 1 edition April 17, 2006
Language: English
ISBN-10: 3527312587
ISBN-13: 978-3527312580
Product Dimensions:
9.5 x 6.9 x 1.1 inches
Shipping Weight: 2.4 pounds
Product Review
"This volume makes an excellent case for initiating, continuing, or broadening studies to identify voltage-gated ion channel agonists. [] Given these findings and the advances made in developing more rapid and reliable lead validation assays, this volume should be of interest to a broad range of medicinal chemists and pharmacologists." (Journal of Medicinial Chemistry, August 24, 2006)
"The present book will be indispensable for all libraries of pharmaceutical companies. University libraries and researchers with an interest in the subject will also certainly wish to acquire this book." (Angewandte Chemie)
Product Description
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.
After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.
For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
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Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry)
Available from Amazon
Price: $204.20
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