by Stephen L. Archer and Nancy J. Rusch
Sales Rank: 2828568
List Price: $183.00 $145.81 At Amazon
Hardcover: 932 pages
Publisher: Springer; 1 edition May 2001
Language: English
ISBN-10: 0306464020
ISBN-13: 978-0306464027
Product Dimensions:
10.1 x 7.2 x 2.3 inches
Shipping Weight: 4.4 pounds
Product Description
Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are becoming a hot topic in physiology. K+ channels determine or modulate many functions of vascular smooth muscle, endothelial and inflammatory cells, and thus are central to regulation of arterial tone and control of cell proliferation. They are also promising targets for antihypertensive treatments with drugs which open and close specific types of K+ channels, making for an active field of research. With their ability to control vascular tone, voltage-gated K+ channels play a significant role in both pulmonary and systemic hypertension as well as in cardiac arrhythmias. This book will highlight the latest discoveries by leading researchers pertaining to the role of K+ channels in the heart and blood vessels in normal physiology and a variety of disease states.
Customer Reviews & Comments This is the most comprehensive read on K+ channels I've ever seen.